2022 | 2021 | Name | Country | 2022 | 2021 | 2022 | 2021 |
|---|---|---|---|---|---|---|---|
| 1 | 1 | Johnson & Johnson | United States | $13,379M | $10,751M | AAA | AA |
| 2 | 2 | Roche | Switzerland | $8,964M | $7,705M | AAA- | AA |
| 3 | 7 | Pfizer | United States | $6,342M | $4,026M | AAA | AA |
| 4 | 12 | AstraZeneca | United Kingdom | $5,607M | $3,174M | AAA- | AA- |
| 5 | 4 | Bayer | Germany | $5,451M | $4,461M | AAA- | AA- |
| 6 | 3 | AbbVie | United States | $5,042M | $4,976M | AA+ | AA |
| 7 | 6 | Merck & Co | United States | $4,632M | $4,113M | AA+ | AA- |
| 8 | 5 | Bristol-Myers Squibb | United States | $4,624M | $4,140M | AA+ | AA |
| 9 | 8 | GSK | United Kingdom | $4,461M | $3,467M | AA | AA- |
| 10 | 10 | Sanofi | France | $4,056M | $3,240M | AA | AA- |
| 11 | 9 | Novartis | Switzerland | 🔒 | 🔒 | 🔒 | 🔒 |
| 12 | 11 | Sinopharm | China | 🔒 | 🔒 | 🔒 | 🔒 |
| 13 | 13 | Lilly | United States | 🔒 | 🔒 | 🔒 | 🔒 |
| 14 | 14 | Amgen | United States | 🔒 | 🔒 | 🔒 | 🔒 |
| 15 | 15 | Novo Nordisk | Denmark | 🔒 | 🔒 | 🔒 | 🔒 |
| 16 | 16 | Takeda | Japan | 🔒 | 🔒 | 🔒 | 🔒 |
| 17 | 17 | Gilead Sciences | United States | 🔒 | 🔒 | 🔒 | 🔒 |
| 18 | 19 | Guangzhou Pharmaceutical | China | 🔒 | 🔒 | 🔒 | 🔒 |
| 19 | 18 | Merck | Germany | 🔒 | 🔒 | 🔒 | 🔒 |
| 20 | 21 | Biogen | United States | 🔒 | 🔒 | 🔒 | 🔒 |
| 21 | 20 | SPH | China | 🔒 | 🔒 | 🔒 | 🔒 |
| 22 | null | Jointown Pharmaceutical | China | 🔒 | 🔒 | 🔒 | 🔒 |
| 23 | 22 | Teva | Israel | 🔒 | 🔒 | 🔒 | 🔒 |
| 24 | 23 | CSL | Australia | 🔒 | 🔒 | 🔒 | 🔒 |
| 25 | 25 | Yunnan Baiyao | China | 🔒 | 🔒 | 🔒 | 🔒 |