2021 | 2020 | Name | Country | 2021 | 2020 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| 1 | 1 | Johnson & Johnson | United States | $10,751M | $10,879M | AA | AA+ |
| 2 | 2 | Roche | Switzerland | $7,705M | $7,592M | AA | AAA- |
| 3 | 10 | AbbVie | United States | $4,976M | $3,420M | AA | AA |
| 4 | 3 | Bayer | Germany | $4,461M | $5,149M | AA- | AA+ |
| 5 | 13 | Bristol-Myers Squibb | United States | $4,140M | $2,251M | AA | AA+ |
| 6 | 5 | Merck & Co | United States | $4,113M | $4,296M | AA- | AA |
| 7 | 6 | Pfizer | United States | $4,026M | $3,814M | AA | AA |
| 8 | 8 | GSK | United Kingdom | $3,467M | $3,519M | AA- | AA |
| 9 | 11 | Novartis | Switzerland | $3,291M | $3,228M | AA- | AA |
| 10 | 9 | Sanofi | France | $3,240M | $3,475M | AA- | AA |
| 11 | 15 | Sinopharm | China | 🔒 | 🔒 | 🔒 | 🔒 |
| 12 | 12 | AstraZeneca | United Kingdom | 🔒 | 🔒 | 🔒 | 🔒 |
| 13 | 14 | Eli Lilly and Company | United States | 🔒 | 🔒 | 🔒 | 🔒 |
| 14 | 17 | Amgen | United States | 🔒 | 🔒 | 🔒 | 🔒 |
| 15 | 18 | Novo Nordisk | Denmark | 🔒 | 🔒 | 🔒 | 🔒 |
| 16 | 16 | Takeda | Japan | 🔒 | 🔒 | 🔒 | 🔒 |
| 17 | 19 | Gilead Sciences | United States | 🔒 | 🔒 | 🔒 | 🔒 |
| 18 | 21 | Merck KGaA | Germany | 🔒 | 🔒 | 🔒 | 🔒 |
| 19 | null | Guangzhou Pharmaceuticals Corporation | China | 🔒 | 🔒 | 🔒 | 🔒 |
| 20 | 24 | SPH | China | 🔒 | 🔒 | 🔒 | 🔒 |
| 21 | 20 | Biogen | United States | 🔒 | 🔒 | 🔒 | 🔒 |
| 22 | 25 | Teva | Israel | 🔒 | 🔒 | 🔒 | 🔒 |
| 23 | null | CSL | Australia | 🔒 | 🔒 | 🔒 | 🔒 |
| 24 | null | Sandoz | Germany | 🔒 | 🔒 | 🔒 | 🔒 |
| 25 | null | Yunnan Baiyao | China | 🔒 | 🔒 | 🔒 | 🔒 |